(1) Propolis contains a variety of terpenoids, diterpenes, and triterpenoids, among which diterpenoids not only have specific killing properties on cancer, but also reduce adverse reactions caused by radiotherapy and chemotherapy; glycosides in polysaccharide substances substances, especially B1-3 glucan, caffeic acid B-phenethyl ester (PEc), lignin in benzoquinone compounds, caffeic acid phenethyl ester (CAPE), isoprene in lipid compounds Compounds such as esters, some of these compounds can directly kill cancer cells, some can enhance human immune function (some patients' white blood cells can increase to about 5,000 after taking propolis tincture around 2,000 for a period of time), and some can adjust the human body. Homeostatic mechanism (BRM), some have antiviral and antioxidant effects;
After years of experiments, scientists have found the superantigen (PRCA) from the anticancer components of supercritical propolis, which is hailed by the WHO as a "response factor for inducing apoptosis in cancer cells". The natural combination and synergistic effect of these substances in propolis endows propolis with better anti-cancer effects.
(2) Studies have found that nitrosamines and Aspergillus flavus are high carcinogens. Pickled foods that are eaten daily are prone to produce nitrite, which can synthesize carcinogenic nitrosamines under the action of gastric acid or bacteria. The phenolic compounds, selenium, vitamin E and B-carotene in propolis can block the synthesis of ammonium nitrite in the body.
(3) Caffeic acid phenethyl ester, caffeine and other components in propolis have the effect of anti-cancer cell proliferation; caffeic acid phenethyl ester (CAPE) and terpenes can control the reproduction of cancer cells and make them stay in the In the DNA synthesis stage, it can inhibit the metabolism of cancer substances, enhance the activity of normal cells, decompose the fibrin around cancer cells, and prevent normal cells from becoming cancerous and metastasizing.
(4) Many oxygen free radicals (OFR) and lipid peroxides (LPO) are produced in the body's metabolism, which can cross-link DNA damage and cause gene mutation. The flavonoid caffeic acid phenethyl ester in propolis can scavenge active oxidative substances and inhibit xanthine oxidase XO, and has a strong inhibitory effect on melanoma, colon cancer and gastric cancer cell lines.
Superoxide dismutase (SOD), quercetin, rhamnetin, kaempferol and other active substances are high in content, have strong inhibitory effect on mutant substances, and are effective ingredients for scavenging free radicals and lipid peroxides. Therefore, it has significant effects on the proliferation of cancer cells, preventing cancer cells from becoming cancerous, enhancing the immune function of the body, and radiotherapy and chemotherapy after cancer surgery.
(5) Scientists analyzed and studied propolis samples from China, Italy and Argentina by gas chromatography and found that coumaric acid, benzyl caffeate, benzyl ferulic acid, isopentyl ferulic acid, Gingerin and jossin have high inhibitory effects on cold virus, herpes virus, Staphylococcus aureus, Escherichia coli, and Candida albicans, especially can kill Helicobacter pylori, inhibit urease activity, promote gastric secretion, and reduce the occurrence of gastric diseases .
(6) Styrene acid and caffeic acid in propolis have obvious inhibitory effects on red blood cells. Propolis extract can stimulate gamma globulin activity, increase antibody production, and enhance the phagocytic ability of macrophages (especially for Gram virus infection) Although it does not have antigenic properties, it can act as an immune adjuvant, thereby improving the body's resistance and inhibiting the growth of cancer cells.
(7) The trace element selenium (Se) in propolis has the effect of activating the immune system and preventing cancer. Studies have found that the level of blood selenium in the human body is closely related to the occurrence of cancer. The combination of selenium and vitamin E, B-carotene I- can enhance the body's immune function, resist oxidation, delay aging, and effectively inhibit the growth of cancer. , has a good adjuvant improvement effect on patients after surgery and radiotherapy and chemotherapy.
The anti-cancer effect of propolis is multi-faceted, because many active components in propolis can enhance the phagocytic function of leukocytes and macrophages, increase the content of total serum protein and globulin, and have biological response regulation BRM (meaning that it has its own adaptation. The environment maintains the balance of physical energy and metabolism), showing a strong immune recovery effect. After the patient takes propolis for a period of time, it will produce antibodies to enhance the autoimmune function, improve the patient's disease resistance, and significantly reduce cancer cells.
